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The Truth About Isopropyl Cloprostenate

With a rise in the popularity of lash serums, there's been an influx of new information on the subject. But sorting out what’s true from what’s not? Now, that can be tricky. As a trusted leader in beauty, we care that our community has accurate information regarding our best-selling GrandeLASH-MD Lash Enhancing Serum so that you can make an informed decision when it comes to investing in your Grande journey.

What is Isopropyl Cloprostenate?

Isopropyl Cloprostenate or "IC" is one of our key ingredients featured in our enhancing serums. It is a type of prostaglandin analogue that is known for hair conditioning, as defined by INCI.

Did you know? INCI is a cosmetic ingredient dictionary & the beauty industry’s standard for recognizing and classifying cosmetic ingredients worldwide.

Why does GrandeLASH-MD utilize IC?
Not all lash serums are created equally. We never settle for lackluster results & Isopropyl Cloprostenate, in conjunction with other synergistic ingredients found within our formulas, is the gold standard for the real, undeniable results you know & love.

Is Isopropyl Cloprostenate a Hormone?

Isopropyl Cloprostenate, is NOT a hormone.

Hormones are chemical messengers produced within the human body - whereas Isopropyl Cloprostenate is a safe, synthetic cosmetic ingredient listed in the cosmetic ingredient dictionary, INCI, as a hair conditioner.

Is Synthetic Bad?

This is a common misconception. Synthetic simply means that the ingredient has been created in a lab.

In fact, synthetic forms can even be superior because there is greater control over their formulation.

Many ingredients you know and love are synthetic. For example, retinol is a form of vitamin A that is also synthetic, or lab-derived.

Does IC Cause Periorbital Fat Loss or Iris Color Change?

GrandeLASH-MD is safe and does not cause iris color change or orbital fat loss.

This has been scientifically substantiated by an 8 month long, third-party clinical study that followed 120 users of GrandeLASH-MD (a study that few cosmetic brands bother to invest in).


In fact, GrandeLASH-MD is amongst the most studied cosmetic lash serums on the market.

GrandeLASH-MD's Key Ingredients

Isopropyl Cloprostenate (I.C)
A prostaglandin analogue that helps to enhance the appearance of eyelashes
Radish Root Ferment
Peptide-packed for conditioning properties
Hyaluronic Acid
Aids lash hydration & can hold up to 1000x its weight in water
Grape Seed Extract
An antioxidant, rich in vitamin E essential for lash health
Amino Acids
The building blocks of collagen & essential to healthy, fortified lashes
Honey & Aloe Vera
A nourishing extract blend to soothe lashes & skin